MMT5-14

• Target:

  Others|||SARS-CoV

• Related Pathways:

  Others|||Microbiology/Virology

• Bioactivity:

  MMT5-14 is a SARS-CoV-2 inhibitor. MMT5-14 showed 2- to 7-fold higher antiviral activity in four variants of SARS-CoV-2. By reducing premature hydrolysis in hamsters, MMT5-14 increased the prodrug concentration by 200- to 300-fold in the plasma and lungs but also enhanced lung accumulation of the active metabolite triphosphate nucleosides (NTP) by 5-fold.

• Smiles:

  C(#N)[C@]1(O[C@H](COP(OC2=CC=CC=C2)(N[C@H](C(OCCCCCCCC/C=C\C/C=C\CCCCC)=O)C)=O)[C@@H](O)[C@H]1O)C=3N4C(=CC3)C(N)=NC=N4

• Molecular Formula:

  C39H55N6O8P

• Molecular Weight:

  766.86

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2719679-31-7