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Enzastaurin 2HCl

CAT: 0931-T69354-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69354-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
365253-37-8
Target
PKC, Others, Autophagy, Apoptosis
Related Pathways
Chromatin/Epigenetic, Apoptosis, Others, Autophagy, Cytoskeletal Signaling
Bioactivity
Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) -stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
Smiles
O=C1C(C=2C=3C(N(C2)C4CCN(CC5=CC=CC=N5)CC4)=CC=CC3)=C(C(=O)N1)C=6C=7C(N(C)C6)=CC=CC7.Cl.Cl
Molecular Formula
C32H31Cl2N5O2
Molecular Weight
588.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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