EG01377 2HCl

• Target:

  Complement System

• Related Pathways:

  Immunology/Inflammation

• Purity:

  0.9956

• Bioactivity:

  EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 ?M and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.

• Smiles:

  N=C (N) NCCC[C@@H] (C (O) =O) NC (C (SC=C1) =C1NS (=O) (C2=C3C (CCO3) =CC (C4=CC=C (C=C4) CN) =C2) =O) =O.Cl.Cl

• Molecular Formula:

  C26H32Cl2N6O6S2

• Molecular Weight:

  659.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2749438-61-5