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Verrucarin J

CAT: 0931-T69225-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69225-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4643-58-7
Target
ROS, Antifungal, Reactive Oxygen Species, Anti-infection, Apoptosis, Others, Virus Protease, Antibiotic
Related Pathways
Microbiology/Virology, Apoptosis, Immunology/Inflammation, Metabolism, NF-κB, Others
Bioactivity
Verrucarin J (Muconomycin B), derived from the Myrothecium fungus family, effectively generates reactive oxygen species (ROS) to induce apoptosis in various cancer cell lines, including A549, HCT 116, and SW-620. Besides its anticancer properties, it exhibits antifungal activity against Candida albicans and Mucor miehei. Furthermore, it notably inhibits the arenavirus Junin (JUNV) yield with an IC 50 of 1.2 ng/mL.
Smiles
CC1=CC2OC3CC4OC(=O)\C=C/C=C/C(=O)OCC\C(C)=C\C(=O)OCC2(CC1)C4(C)C31CO1
Molecular Formula
C27H32O8
Molecular Weight
484.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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