Products for Research Use Only

AZD-6918

CAT: 0931-T68403-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T68403-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
905585-60-6
Target
Trk receptor, Others
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth.
Smiles
N([C@@H](C)C1=CC=C(F)C=C1)C2=C(C#N)C=C(F)C(NC=3C=C(OC(C)C)NN3)=N2
Molecular Formula
C20H20F2N6O
Molecular Weight
398.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C