AZD-6918

• Target :

  Trk receptor|||Others

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Others

• Bioactivity :

  AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth.

• Smiles :

  N([C@@H](C)C1=CC=C(F)C=C1)C2=C(C#N)C=C(F)C(NC=3C=C(OC(C)C)NN3)=N2

• Molecular Formula :

  C20H20F2N6O

• Molecular Weight :

  398.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  905585-60-6