BMS-751324

• Target:

  P38 MAPK|||Others|||TNF

• Related Pathways:

  Apoptosis|||MAPK|||Others

• Bioactivity:

  BMS-751324, a p38? MAPK inhibitor, features a carbamyl-methyl linkage precursor with esters and phosphate functional groups from hydroxyphenylacetic acid (HPA) . It effectively reduces foot swelling and suppresses LPS-induced TNF? production in an arthritic rat model.

• Smiles:

  N(C=1C=2N(C=C(C(N(C(OCOC(CC3=CC=C(OP(=O)(O)O)C=C3)=O)=O)CCC)=O)C2C)N=CN1)C4=CC(C(NC5CC5)=O)=CC=C4C

• Molecular Formula:

  C32H35N6O10P

• Molecular Weight:

  694.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  948842-66-8