BMS-751324

• CAS Number :

  948842-66-8

• Target :

  P38 MAPK|||Others|||TNF

• Related Pathways :

  Apoptosis|||MAPK|||Others

• Bioactivity :

  BMS-751324, a p38? MAPK inhibitor, features a carbamyl-methyl linkage precursor with esters and phosphate functional groups from hydroxyphenylacetic acid (HPA) . It effectively reduces foot swelling and suppresses LPS-induced TNF? production in an arthritic rat model.

• Smiles :

  N(C=1C=2N(C=C(C(N(C(OCOC(CC3=CC=C(OP(=O)(O)O)C=C3)=O)=O)CCC)=O)C2C)N=CN1)C4=CC(C(NC5CC5)=O)=CC=C4C

• Molecular Formula :

  C32H35N6O10P

• Molecular Weight :

  694.63

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C