WDR5-IN-5

• Target:

  Others|||Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic|||Others

• Bioactivity:

  WDR5-IN-5 is a selective, orally active inhibitor targeting the WD repeat domain 5 (WDR5) WIN site.WDR5-IN-5 exhibits high affinity for WDR5 (Ki<0.02 nM) .WDR5-IN-5 exhibits anti-cancer cell proliferation and a good pharmacokinetic profile.

• Smiles:

  C(F)(F)(F)C=1C(C2=C3C(C(=O)N([C@@H]([C@H]4CC4)C5=CC(C)=CC=N5)CC3)=CC(CN6C=CN=C6)=C2)=CN(CC)N1

• Molecular Formula:

  C29H29F3N6O

• Molecular Weight:

  534.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2417012-26-9