WDR5-IN-5

• Target :

  Others|||Histone Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic|||Others

• Bioactivity :

  WDR5-IN-5 is a selective, orally active inhibitor targeting the WD repeat domain 5 (WDR5) WIN site.WDR5-IN-5 exhibits high affinity for WDR5 (Ki<0.02 nM) .WDR5-IN-5 exhibits anti-cancer cell proliferation and a good pharmacokinetic profile.

• Smiles :

  C(F)(F)(F)C=1C(C2=C3C(C(=O)N([C@@H]([C@H]4CC4)C5=CC(C)=CC=N5)CC3)=CC(CN6C=CN=C6)=C2)=CN(CC)N1

• Molecular Formula :

  C29H29F3N6O

• Molecular Weight :

  534.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2417012-26-9