PROTAC (H-PGDS) -7

• Target :

  Prostaglandin Receptor|||Molecular Glues|||Others

• Related Pathways :

  Immunology/Inflammation|||Others|||PROTAC|||GPCR/G Protein

• Bioactivity :

  PROTAC (H-PGDS) -7 is a selective and potent small molecule hematopoietic prostaglandin D synthase (H-PGDS) PROTAC degradation agent that exhibits degradation activity in KU812 cells with a DC50 of 17.3 pM. It effectively inhibits prostaglandin D2 (PGD2) and is a candidate compound for the treatment of DMD and other H-PGDS-related diseases.

• Smiles :

  O=C1C2=C(C=CC=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(C(=O)C5CCN(CC5)C6=CC=C(NC(=O)C=7C=NC(OC8=CC=CC=C8)=NC7)C=C6)CC4

• Molecular Formula :

  C40H38N8O7

• Molecular Weight :

  742.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2761281-50-7