Products for Research Use Only

ACHP

CAT: 0931-T22021-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T22021-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
406208-42-2
Target
Apoptosis, IκB/IKK, STAT
Related Pathways
Apoptosis, Stem Cells, NF-κB, JAK/STAT signaling
Purity
0.9877
Bioactivity
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR) -driven gene expression through inhibition of NF-κB activation, inhibits TNF-α-induced NF-κB (p65) recruitment to the HIV-1 LTR, and inhibits TNF-α-induced NF-κB (p65) recruitment to the HIV-1 LTR. ACHKP has anti-HIV-1 activity and inhibits TNF-α-induced recruitment of NF-κB (p65) to the HIV-1 LTR.
Smiles
N#CC1=C(N=C(C=C1C2CCNCC2)C=3C(O)=CC=CC3OCC4CC4)N
Molecular Formula
C21H24N4O2
Molecular Weight
364.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C