ACHP

CAT: 0931-MF-0061746-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0061746-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
406208-42-2
Target
Apoptosis|||I?B/IKK|||STAT
Related Pathways
Apoptosis|||Stem Cells|||NF-?B|||JAK/STAT signaling
Purity
0.9877
Bioactivity
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-? and IKK-?. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR) -driven gene expression through inhibition of NF-?B activation, inhibits TNF-?-induced NF-?B (p65) recruitment to the HIV-1 LTR, and inhibits TNF-?-induced NF-?B (p65) recruitment to the HIV-1 LTR. ACHKP has anti-HIV-1 activity and inhibits TNF-?-induced recruitment of NF-?B (p65) to the HIV-1 LTR.
Smiles
N#CC1=C(N=C(C=C1C2CCNCC2)C=3C(O)=CC=CC3OCC4CC4)N
Molecular Formula
C21H24N4O2
Molecular Weight
364.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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