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αMβ2 integrin agonist-1

CAT: 0013-GTR19265046-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19265046-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
αMβ2integrinagonist-1 (Compound 8) is a highly selective αMβ2 integrin agonist with anti-inflammatory properties (EC50=1.4 nM) . It activates integrin-mediated cell adhesion and the JNK/ERK signaling pathway. Additionally, αMβ2integrinagonist-1 induces polarization of tumor-associated macrophages and enhances antitumor T-cell immune responses. This compound holds potential for research in cancer and chronic inflammatory diseases such as pancreatic cancer and rheumatoid arthritis.
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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