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6PGD-IN-2

CAT:
931-T212075-01
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
6PGD-IN-2 - image 1

6PGD-IN-2

  • Target:

    DNA/RNA Synthesis

  • Related Pathways:

    Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

  • Bioactivity:

    6PGD-IN-2 is a non-competitive inhibitor of 6-phosphogluconate dehydrogenase (6PGD) with an IC50 value of 5.1 ?M. It disrupts 6PGD oligomerization in a substrate-dependent manner and induces the production of NADPH and Ru-5-P while reducing DNA synthesis in A549 cells. 6PGD-IN-2 is applicable in research on non-small cell cancer and liver cancer.

  • Shipping Conditions:

    Cool pack

  • Storage Temperature:

    -20°C

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HY-1754926PGD-IN-2
MBS3616422-016PGD-IN-S3
HY-N7850-016PGD-IN-1
M27840-016PGD-IN-S3
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