PKI-166

CAT: 0931-T16549-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T16549-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
187724-61-4
Target
EGFR|||VEGFR
Related Pathways
Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Purity
0.998
Bioactivity
PKI-166 is an oral inhibitor of EGF-R tyrosine kinase (IC50:0.7 nM) that is both effective and selective. PKI-166 can effectively inhibit the growth and metastasis of various human cancer cells including pancreatic cancer.
Smiles
C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1
Molecular Formula
C20H18N4O
Molecular Weight
330.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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