PKI-166

• Target:

  EGFR|||VEGFR

• Related Pathways:

  Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

• Purity:

  0.998

• Bioactivity:

  PKI-166 is an oral inhibitor of EGF-R tyrosine kinase (IC50:0.7 nM) that is both effective and selective. PKI-166 can effectively inhibit the growth and metastasis of various human cancer cells including pancreatic cancer.

• Smiles:

  C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1

• Molecular Formula:

  C20H18N4O

• Molecular Weight:

  330.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  187724-61-4