PKI-166

• Target :

  EGFR|||VEGFR

• Related Pathways :

  Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

• Purity :

  0.998

• Bioactivity :

  PKI-166 is an oral inhibitor of EGF-R tyrosine kinase (IC50:0.7 nM) that is both effective and selective. PKI-166 can effectively inhibit the growth and metastasis of various human cancer cells including pancreatic cancer.

• Smiles :

  C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1

• Molecular Formula :

  C20H18N4O

• Molecular Weight :

  330.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  187724-61-4