JPHM-2-167

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Chromatin/Epigenetic|||Metabolism

• Bioactivity :

  PHM-2-167 (Compound 11) is a selective inhibitor of the prolyl hydroxylase domain enzyme (PHD) . It inhibits PHD2 and PHD3 with IC50 values of 0.253 ?M and 3.95 ?M, respectively. PHM-2-167 is applicable for research in chronic kidney disease.

• Smiles :

  O=C1N(C=2C=CC(=CC2)C=3C=CC=CC3)C(=O)C4(N1C5=NC=CC=N5)CCN(CC6=NC=CC=C6C)CC4

• Molecular Formula :

  C30H28N6O2

• Molecular Weight :

  504.582

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1258877-17-6