DHC-286

• CAS Number :

  2920443-08-7

• Target :

  Molecular Glues

• Related Pathways :

  PROTAC

• Bioactivity :

  DHC-286 is a molecular glue degrader that targets GSPT1. It recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, facilitating its ubiquitination and subsequent degradation via the proteasome, which induces cytotoxic effects. DHC-286 holds potential for cancer research.

• Smiles :

  O=C(NCC=1C=CC=CC1C(F)(F)F)COC2=CC=C3C(=O)N(CC3=C2)C4C(=O)NC(=O)CC4

• Molecular Formula :

  C23H20F3N3O5

• Molecular Weight :

  475.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C