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KPC-2-IN-3

CAT: 0013-GTR19263848-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263848-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with an IC50 of 0.533 μM and a Ki of 0.194 μM. It works synergistically with Meropenem to exhibit antibacterial activity against carbapenem-resistant K. pneumoniae K47-25, reducing bacterial count and demonstrating a post-antibiotic effect. Additionally, KPC-2-IN-3 significantly decreases lung bacterial load in a mouse pneumonia model.
Field of Research
Infectious Disease & Virology
Storage Conditions
-20°C
Notes
For research use only.

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