Products for Research Use Only

SHP2-IN-38

CAT: 0931-T211281-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211281-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, ERK, Phosphatase
Related Pathways
Others, MAPK, Metabolism
Bioactivity
SHP2-IN-38 is an innovative green fluorescent inhibitor targeting SHP2, exhibiting IC50 values as follows: 2.89 μM (SHP2), 8.73 μM (SHP1), 11.08 μM (PTP1B), and 33.07 μM (TCPTP) . It impedes the SHP2-mediated ERK signaling pathway and inhibits MV4-11 cell proliferation in vitro with an IC50 of 7.90 μM. The excitation wavelength of SHP2-IN-38 is 360 nm, with a maximum emission wavelength of 550 nm in DMSO and 540 nm in DMF. Additionally, it demonstrates green fluorescent imaging in HeLa cells and zebrafish.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C