GPR84 agonist-2

CAT: 0931-MF-0118395-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0118395-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
GPCR
Related Pathways
Endocrinology/Hormones|||GPCR/G Protein
Bioactivity
GPR84agonist-2 (Compound 8e) is a highly selective GPR84 agonist with an EC50 value of 7.24 nM. It activates the G?q signaling pathway, leading to the production of inositol triphosphate (IP3) and the release of calcium ions. This compound enhances the chemotaxis of neutrophils and the release of pro-inflammatory cytokines, making it a promising candidate for research into inflammatory diseases such as ulcerative colitis and acute lung injury.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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