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MSN-125

CAT: 0931-T16155-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T16155-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1592908-16-1
Target
Akt, Apoptosis, Bcl-2 Family
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Bioactivity
MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) (IC50: 4 μM) .
Smiles
COCCOCOc1ccc2[C@@H]([C@@H](CN)Oc2c1)N(Cc1ccc(Br)cc1)C(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
Molecular Formula
C36H38BrN3O6
Molecular Weight
688.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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