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CYP1B1-IN-9

CAT: 0931-T211184-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211184-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3077254-39-5
Target
Cytochromes P450
Related Pathways
Metabolism
Bioactivity
CYP1B1-IN-9 is a highly selective and competitive CYP1B1 inhibitor, with IC50 values of 1.48 nM for CYP1B1, and greater than 100 μM and 80 μM for CYP1A1 and CYP1A2, respectively. This compound effectively inhibits the migration and invasion of A549/T cells, offers the potential to resensitize paclitaxel-resistant cells, and exhibits good metabolic stability and safety, as well as favorable pharmacokinetic properties. CYP1B1-IN-9 is applicable in research on tumor resistance.
Smiles
O=C(NC=1C=C(Cl)C=C(Cl)C1)C2=NC(=CS2)C=3C=CC=C(Cl)C3
Molecular Formula
C16H9Cl3N2OS
Molecular Weight
383.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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