LC-PDin06

• Target:

  ROS

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  LC-PDin06, a selective PRDX1 inhibitor with an IC50 of 0.042 ?M, is a derivative of Celastrol. It exhibits potent anti-proliferative effects on colorectal cancer cells by significantly increasing ROS levels.

• Smiles:

  C[C@@]12[C@](C)([C@]3([C@@](C)(CC1)CC[C@](C(NCCCN4C=CN=C4)=O)(C)C3)[H])CC[C@]5(C)C2=CC=C6C5=CC(=O)C(O)=C6C

• Molecular Formula:

  C35H47N3O3

• Molecular Weight:

  557.77

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2027514-32-3