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AAK1-IN-8

CAT: 0931-T210876-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210876-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2969205-90-9
Target
Serine/threonin kinase, AAK1 (AP2 associated kinase 1)
Related Pathways
Cell Cycle/Checkpoint, Neuroscience, Metabolism
Bioactivity
AAK1-IN-8 (Compound 18) is a broad-spectrum NAK inhibitor. It effectively inhibits AAK1 and GAK with EC50 values of 50 nM and 190 nM, respectively, and prevents the phosphorylation of the AP2-μ2 subunit at threonine 156 (T156) .
Smiles
O=C(NCC=1C=CC=CC1)C2=CC=C3C=C2OCCOCCN=C4C=CN5N=CC3=C5N4
Molecular Formula
C24H23N5O3
Molecular Weight
429.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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