PF-06442609

CAT: 0931-T210322-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T210322-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1402002-76-9

Target

Gamma-secretase

Related Pathways

Neuroscience, Stem Cells, Proteases/Proteasome

Bioactivity

PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.

Smiles

O=C1N2C(C(=O)N([C@H](COC3=C([C@H](C(F)(F)F)C)C=C(F)C=C3)C)CC2)=CC=C1N4C=NC(C)=C4

Molecular Formula

C24H24F4N4O3

Molecular Weight

492.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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