CB-0821

• Target :

  HIV Protease|||CCR

• Related Pathways :

  GPCR/G Protein|||Proteases/Proteasome|||Immunology/Inflammation|||Microbiology/Virology

• Bioactivity :

  CB-0821 is a high-affinity CCR5 inhibitor with a Ki of 0.04 nM. It effectively binds to the hydrophobic pocket of the CCR5 protein, hindering the interaction between viral proteins and CCR5, thereby blocking virus entry. CB-0821 holds potential for anti-HIV research.

• Smiles :

  N1=C2N=C(C=C(C=3C=CC=CC3)N2N=C1CC=4N=C5N=C(C=C(C=6C=CC=CC6)N5N4)C=7C=CC=CC7)C=8C=CC=CC8

• Molecular Formula :

  C35H24N8

• Molecular Weight :

  556.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  81430-62-8