MC-ND-18

• Target:

  NOD-like Receptor (NLR) |||ATTECs

• Related Pathways:

  Immunology/Inflammation|||PROTAC

• Bioactivity:

  MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.

• Molecular Formula:

  C42H42Br2IN3O9S

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C