Products for Research Use Only

LC-MI-3

CAT: 0931-T209930-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209930-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, IRAK, NF-κB
Related Pathways
PROTAC, NF-κB, Immunology/Inflammation
Bioactivity
LC-MI-3 is an orally active and potent PROTAC degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), with a DC50 value of 47.3 nM. It effectively inhibits the activation of downstream NF-κB signaling. LC-MI-3 is applicable for research in both acute and chronic inflammatory skin conditions.
Molecular Formula
C39H36N8O8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C