PRDX1-IN-2

• Target:

  Apoptosis|||ROS Kinase

• Related Pathways:

  Apoptosis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  PRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) with an IC50 of 0.35 ?M. It reduces mitochondrial membrane potential in SW620 cells, potentially due to increased ROS resulting from PRDX1 inhibition, leading to apoptosis. PRDX1-IN-2 is applicable in colorectal cancer research.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C