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PRDX1-IN-2

CAT: 0931-T209850-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209850-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, ROS Kinase
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors
Bioactivity
PRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) with an IC50 of 0.35 μM. It reduces mitochondrial membrane potential in SW620 cells, potentially due to increased ROS resulting from PRDX1 inhibition, leading to apoptosis. PRDX1-IN-2 is applicable in colorectal cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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