PRDX1-IN-3

• Target:

  MDM-2/p53|||Reactive Oxygen Species

• Related Pathways:

  Immunology/Inflammation|||Apoptosis|||NF-?B|||Metabolism

• Bioactivity:

  PRDX1-IN-3 (SOMCL-19-048) is a PRDX1 covalent inhibitor with anti-colorectal cancer activity. PRDX1-IN-3 can effectively inhibit the proliferation of colorectal cancer cells and significantly reduce the anti-tumor effect on colorectal cancer nude mice carrying PRDX1 gene knockout. PRDX1-IN-3 can also upregulate downstream genes of the p53 signaling pathway and exert anti-cancer effects.

• Smiles:

  C[C@@]12[C@] (C) ([C@]3 ([C@@] (C) (CC1) CC[C@] (NC (N[C@H] (C (OC) =O) C) =O) (C) C3) [H]) CC[C@]4 (C) C2=CC=C5C4=CC (=O) C (O) =C5C

• Molecular Formula:

  C33H46N2O5

• Molecular Weight:

  550.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2566976-46-1