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PRDX1-IN-3

CAT: 0931-T203007-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203007-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2566976-46-1
Target
MDM-2/p53, Reactive Oxygen Species
Related Pathways
Immunology/Inflammation, Apoptosis, NF-κB, Metabolism
Bioactivity
PRDX1-IN-3 (SOMCL-19-048) is a PRDX1 covalent inhibitor with anti-colorectal cancer activity. PRDX1-IN-3 can effectively inhibit the proliferation of colorectal cancer cells and significantly reduce the anti-tumor effect on colorectal cancer nude mice carrying PRDX1 gene knockout. PRDX1-IN-3 can also upregulate downstream genes of the p53 signaling pathway and exert anti-cancer effects.
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C[C@@]12[C@](C)([C@]3([C@@](C)(CC1)CC[C@](NC(N[C@H](C(OC)=O)C)=O)(C)C3)[H])CC[C@]4(C)C2=CC=C5C4=CC(=O)C(O)=C5C
Molecular Formula
C33H46N2O5
Molecular Weight
550.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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