PAD4-IN-4

• Target:

  PAD

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  PAD4-IN-4 (compound 28) is a potent PAD4 inhibitor with an IC50 of 0.79±0.09 ?M. It reshapes the neutrophil phenotype, increases the proportion of dendritic cells and M1 macrophages, reduces the number of myeloid-derived suppressor cells, and enhances the tumor immune microenvironment. PAD4-IN-4 is applicable for research in triple-negative breast cancer.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C