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HER2-IN-15

CAT: 0931-T209527-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209527-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
HER2-IN-15 (Compound 1) is a HER2 inhibitor that effectively targets the YVMA HER2 exon 20 insertion mutation (HER2 YVMA) with an IC50 of less than 200 nM. It also inhibits the proliferation of BaF3 cells with the HER2 YVMA mutation, achieving an IC50 of under 200 nM, and contributes to the improvement of non-small cell lung cancer (NSCLC) .
Molecular Formula
C28H29N9O2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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