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MALT1-IN-13

CAT: 0931-T209402-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209402-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, MALT
Related Pathways
Immunology/Inflammation, Apoptosis
Bioactivity
MALT1-IN-13 (compound 10m) is an inhibitor of the mucosa-associated lymphoid tissue lymphoma translocation protein (MALT1), forming a covalent and irreversible bond with the MALT1 protease, thereby inhibiting its activity with an IC50 of 1.7 μM. It suppresses the proliferation of ABC-DLBCL and induces apoptosis in ABC-DLBCL HBL1 cells. Additionally, MALT1-IN-13 regulates the mTOR and PI3K-Akt pathways.
Molecular Formula
C20H15BrClN3O3S2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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