Products for Research Use Only
RegisterLogin

MALT1-IN-6

CAT: 0804-HY-143424Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-143424Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MALT1-IN-6 is a potent MALT1 protease inhibitor with a Ki of 9 nM. MALT1-IN-6 has anticancer effects (WO2018226150A1; Compound 4) [1].
CAS Number
2254669-07-1
UNSPSC
12352005
Target
MALT1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/malt1-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C(C2(C(F)(F)F)CC2)N3C(N=C1)=CC(Cl)=N3)NC4=CC(Cl)=C(N5N=CC=N5)N=C4
Molecular Formula
C18H12Cl2F3N9O
Molecular Weight
498.25
References & Citations
[1]Karolina Ersmark, et al. Pyrazolopyrimidine as malt-1 inhibitors. WO2018226150A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Malt1-IN-6
CAS Number2254669-07-1
PubChem CID142491638
IUPAC Name1-[5-chloro-6-(triazol-2-yl)-3-pyridinyl]-3-[2-chloro-7-[1-(trifluoromethyl)cyclopropyl]pyrazolo[1,5-a]pyrimidin-6-yl]urea
Molecular FormulaC18H12Cl2F3N9O
Molecular Weight498.2
XLogP3.4
Topological Polar Surface Area115
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count4
Heavy Atom Count33
Formal Charge0
Complexity739
SMILES
C1CC1(C2=C(C=NC3=CC(=NN32)Cl)NC(=O)NC4=CC(=C(N=C4)N5N=CC=N5)Cl)C(F)(F)F
InChI
InChI=1S/C18H12Cl2F3N9O/c19-10-5-9(7-25-15(10)32-26-3-4-27-32)28-16(33)29-11-8-24-13-6-12(20)30-31(13)14(11)17(1-2-17)18(21,22)23/h3-8H,1-2H2,(H2,28,29,33)
InChIKey
AAQRMGYKVAIZSL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Malt1-IN-6
CAS: 2254669-07-1
CID: 142491638
Formula: C18H12Cl2F3N9O
MW: 498.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight498.2
XLogP33.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count4
Exact Mass497.0493959
Monoisotopic Mass497.0493959
Topological Polar Surface Area115 Ų
Heavy Atom Count33
Formal Charge0
Complexity739
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-150232MALT1-IN-11
HY-162268MALT1-IN-13
HY-164560MALT1-IN-14
HY-143426MALT1-IN-8
HY-143423MALT1-IN-5
HY-143427MALT1-IN-9
HY-143422MALT1-IN-3
HY-143425MALT1-IN-7
HY-148249NVS-MALT1
HY-143423A(S) -MALT1-IN-5

Alternative Products

CatalogName
MBS5806042MALT1-IN-6
485311MALT1
YP-W200422-01Human MALT1 (MALT1) ELISA Kit
MAB4850Human MALT1 MAb (Clone MALT1-C)
GTR18159889-01MALT1 Antibody
T200726-01MALT1-IN-14
T62533-01MALT1-IN-8
FP-159MALT1/IGH
MBS5805728MALT1-IN-3

Popular Products