SPOP-IN-2

• Target :

  E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination

• Bioactivity :

  SPOP-IN-2 (Compound E1) is a potent inhibitor of speckle-type POZ protein (SPOP), with an IC50 of 0.58 ?M. It disrupts the interaction between SPOP and substrates and selectively inhibits the proliferation of clear cell renal cell carcinoma (ccRCC) .

• Smiles :

  C(O)(=O)C=1N2[C@@]([C@H](NC(=O)C=3OC(CCl)=CC3)C2=O)(SCC1C=C)[H]

• Molecular Formula :

  C15H13ClN2O5S

• Molecular Weight :

  368.79

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3031640-86-2