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SPOP-IN-2

CAT: 0804-HY-161251-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161251-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SPOP-IN-2 (compound E1) is a Speckle-type POZ protein (SPOP) inhibitor with IC50 of 0.58 μM, which disrupt the SPOP-subtrate interaction and selectively inhibits proliferation of ccRCC[1].
CAS Number
3031640-86-2
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/spop-in-2.html
Purity
91.00
Solubility
10 mM in DMSO
Smiles
O=C1[C@@H](NC(C2=CC=C(CCl)O2)=O)[C@@]3([H])SCC(C=C)=C(C(O)=O)N31
Molecular Formula
C15H13ClN2O5S
Molecular Weight
368.79
References & Citations
[1]Zhou C, et al., Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) . ACS Med Chem Lett. 2024 Jan 25;15 (2) :270-279.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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