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AK-HW-90

CAT: 0931-T209003-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209003-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis
Bioactivity
AK-HW-90 (compound 2B) is a potent pan-Bcr-Abl inhibitor that shows significant inhibitory activity against Imatinib-resistant mutants. It inhibits the resistant Bcr-AblT315I mutant with an IC50 of 0.65 nM. AK-HW-90 offers potential anti-cancer properties and can be utilized in chronic myeloid leukemia (CML) research.
Molecular Formula
C27H29N5O2S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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