(+) -JQ1-OH

• Target:

  Drug Metabolite

• Related Pathways:

  Metabolism

• Bioactivity:

  (+) -JQ1-OH is the primary metabolite of (+) -JQ1. (+) -JQ-1 (JQ1) is a potent, specific, and reversible inhibitor of BET bromodomain, with IC50 values of 77 nM for the first bromodomain and 33 nM for the second bromodomain (BRD4 (1/2) ) . Additionally, (+) -JQ-1 stimulates autophagy (autophagy) .

• Molecular Formula:

  C23H25ClN4O3S

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C