β-NF-JQ1

• Target:

  PROTACs|||Epigenetic Reader Domain

• Related Pathways:

  PROTAC|||Chromatin/Epigenetic

• Purity:

  0.9945

• Bioactivity:

  ?-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins. Using ?-NF as an AhR ligand, it targets bromodomain (BRD) -containing proteins and induces AhR and BRD protein interactions. ?-NF-JQ1 exhibits potent anticancer activity associated with protein knockdown activity.

• Smiles:

  CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC4=CC=C(C=C4)C=5OC=6C(C(=O)C5)=C7C(=CC6)C=CC=C7)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C

• Molecular Formula:

  C45H42ClN5O6S

• Molecular Weight:

  816.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2380000-55-3