TRPC6 antagonist-1

• Target:

  TRP/TRPV Channel

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  TRPC6 antagonist-1 (X26) is a TRPC6 inhibitor with IC50 values of 0.97 ?M for TRPC6, 3.93 ?M for TRPC3, 5.77 ?M for TRPC5, and 4.37 ?M for TRPC7. Additionally, TRPC6 antagonist-1 hinders TGF-?1-induced myofibroblast differentiation, thereby mitigating renal fibrosis.

• Molecular Formula:

  C26H32N4O2S

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C