TRPC antagonist 1

CAT: 0931-MF-0116395-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0116395-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3027139-12-1
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
TRPC antagonist1 (compound 15g) is a potent TRP channel (TRPC) antagonist with IC50 values of 2.4 ?M, 12.2 ?M, 7.6 ?M, 2.9 ?M, and 3.4 ?M for TRPC3, TRPC4, TRPC5, TRPC6, and TRPC7, respectively. It demonstrates significant anti-glioblastoma efficacy in vitro against the U87 cell line.
Smiles
O=C(NC1=CC=C(O)C=C1)C=2N=C(SC2)N(CC=3C=CC=4C=CC=CC4C3)CCN
Molecular Formula
C23H22N4O2S
Molecular Weight
418.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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