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EN1441

CAT: 0931-T206982-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206982-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2196448-47-0
Target
Androgen Receptor
Related Pathways
Endocrinology/Hormones
Bioactivity
EN1441 is a covalent degrader that targets the androgen receptor (AR) with an EC50 value of 4.2 μM, as well as its truncated variant AR-V7. It selectively and effectively degrades AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 holds potential for research into androgen-independent prostate cancer.
Smiles
O=C(C=C)N1C2=CC(Cl)=CC=C2NC(=O)C1(C)C
Molecular Formula
C13H13ClN2O2
Molecular Weight
264.708
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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