BMX-IN-3

CAT: 0931-T206981-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206981-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2657662-64-9
Target
Apoptosis|||Autophagy|||BTK
Related Pathways
Tyrosine Kinase/Adaptors|||Apoptosis|||Angiogenesis|||Autophagy
Bioactivity
BMX-IN-3 (B6a) is an irreversible and selective inhibitor of BMX with an IC50 value of 12 nM. It induces cell cycle arrest and apoptosis, triggers protective autophagy, and inhibits the BMX/AKT/mTOR pathway. BMX-IN-3 (B6a) is applicable for research in gastric cancer.
Smiles
N(C=1N=C(NC2=CC(OC3=CC=CC=C3)=CC=C2)N=C(N)N1)[C@H]4CN(S(C=C)(=O)=O)CCC4
Molecular Formula
C22H25N7O3S
Molecular Weight
467.544
Shipping Conditions
Cool pack
Storage Temperature
-20°C