CFTR corrector 18

• Target :

  CFTR

• Related Pathways :

  Membrane transporter/Ion channel

• Bioactivity :

  CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR) . It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF) .

• Smiles :

  C(C12CC(C1)C2)[C@H]3N(CC=4N=C5C(=NC4)OC(C(C)(C)C)=C5)C(=O)C6=CC(S(=O)(=O)NC=7N=C(OC3)C=C(N7)C8=C(C)C=CC=C8C)=CC=C6

• Molecular Formula :

  C38H40N6O5S

• Molecular Weight :

  692.826

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2993441-49-7