ENX-101

• Target:

  GABA Receptor

• Related Pathways:

  Neuroscience|||Membrane transporter/Ion channel

• Bioactivity:

  ENX-101 is an orally active partial positive allosteric modulator (PAM) of the (GABAA) receptor. It selectively targets the ?2?2?2L (EC50= 0.76 nM), ?2?3?2L (EC50= 0.61 nM), ?3 (EC50= 1.97 nM), and ?5 (EC50= 0.85 nM) subunits of the GABA receptor. ENX-101 demonstrates anticonvulsant activity in various animal models.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C