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TTBK1/2-IN-2

CAT: 0931-T206619-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206619-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2857982-35-3
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
TTBK1/2-IN-2 (compound 9) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 384 nM and 175 nM, respectively. In human induced pluripotent stem cells (iPSC), TTBK1/2-IN-2 demonstrates a significant ciliogenesis phenotype.
Smiles
OC(C#CC=1C=CC=2NC3=C(C=4N=C(N=CC4CCC3)N)C2C1)(CC)CC
Molecular Formula
C22H24N4O
Molecular Weight
360.452
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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