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TTBK1-IN-2

CAT: 0931-T60086-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T60086-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2765453-51-6
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Purity
0.9983
Bioactivity
TTBK1-IN-2 (N-[4- (4-chlorophenoxy) phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 μM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
Smiles
Clc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1
Molecular Formula
C18H13ClN4O
Molecular Weight
336.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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