Anticonvulsant agent 10

• Target:

  Nrf2

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C