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Anticonvulsant agent 8

CAT: 0804-HY-170833Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170833Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anticonvulsant agent 8 (compound D4) is an anticonvulsant agent that inhibits GABAA currents with ED50 values of 2.23 and 24.60 mg/kg in the maximum electroshock (MES) and pentylenetetrazol (PTZ) tests in mouse models, respectively[1].
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
C1(C=CC=C2)=C2C=CC(C3=NOC(CN4C=NC=N4)=N3)=C1
Molecular Formula
C15H11N5O
Molecular Weight
277.28
References & Citations
[1]Valipour M, et al. Design, synthesis, and structure-activity relationships of five-membered heterocyclic incorporated aryl (alkyl) azoles: From antiproliferative thiazoles to safer anticonvulsant oxadiazoles. Bioorg Chem. 2025 Feb;155:108117.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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