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15-LOX-IN-2

CAT: 0931-T206249-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206249-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Lipoxygenase, COX, PPAR, Interleukin
Related Pathways
Metabolism, Immunology/Inflammation, DNA Damage/DNA Repair, Neuroscience
Bioactivity
15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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