Tau ligand-1

CAT: 0931-T206168-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T206168-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3063166-64-0

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Bioactivity

Tau ligand-1 (Compound 75) is a ligand of aggregated tau protein that can penetrate the blood-brain barrier. In tissues affected by Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration, and Pick's disease, Tau ligand-1 shows high affinity for aggregated tau protein, with equilibrium dissociation constants (KD) ranging from 1 to 3.8 nM. It holds potential as a positron emission tomography (PET) tracer for imaging studies of tau-related diseases within the central nervous system.

Smiles

FC1=NC(=CC=C1C2=CC=3C=CC=CC3N2)N4CCOCC4

Molecular Formula

C17H16FN3O

Molecular Weight

297.327

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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