CGP-74514

• Target:

  Apoptosis|||CDK

• Related Pathways:

  Apoptosis|||Cell Cycle/Checkpoint

• Purity:

  0.9854

• Bioactivity:

  CGP-74514 (Compound 13) is a highly selective cyclin-dependent kinase 1 (CDK1) inhibitor (IC50=25 nM) . This compound inhibits CDK1/cyclin B complex activity, resulting in G2/M phase cell cycle arrest and induction of tumor cell apoptosis, demonstrating promising applications in bladder cancer research.

• Smiles:

  N(C1=C2C(N(CC)C=N2)=NC(N[C@@H]3[C@H](N)CCCC3)=N1)C4=CC(Cl)=CC=C4

• Molecular Formula:

  C19H24ClN7

• Molecular Weight:

  385.89

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  190653-73-7