FTO-IN-14

CAT: 0931-T205742-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T205742-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

FTO-IN-14 (Compound F97) is an inhibitor of the RNA demethylase Fat mass and obesity-associated protein (FTO), with an IC50 of 0.45 μM. It modulates the expression of the ASB2, RARA, and MYC proteins. FTO-IN-14 demonstrates antiproliferative activity in AML cancer cells, with IC50 values of 0.7-5.5 μM against MOLM13, NB4, HEL, OCI-AML3, MV4-11, and MONOMAC6, and induces apoptosis in NB4 cells. Additionally, FTO-IN-14 exhibits antitumor activity in a mouse NB4 xenograft model.

Smiles

CC(NN=C1C)=C1C2=CC(C3CC3)=C(NC4=C(C(O)=O)SC=C4)C(C5CC5)=C2

Molecular Formula

C22H23N3O2S

Molecular Weight

393.502

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T61152-01	FTO-IN-8
T40221	FTO-IN-2
T63740-01	FTO-IN-4
T204333-01	FTO-IN-13
T27393-01	FTO-IN-7d
T40222-01	FTO-IN-3
T82368-01	FTO-IN-10
T88144-01	FTO-IN-12
T9089-01	FTO-IN-1
T60994-01	FTO-IN-6

Alternative Products

Catalog	Name
GTR19249040-01	FTO-IN-14
523110-01	FTO
YP-W29931-01	Mouse FTO (FTO) ELISA Kit
YP-W76737-01	Canine FTO (FTO) ELISA Kit
YP-W10566-01	Human FTO (FTO) ELISA Kit
YP-W80450-01	Porcine FTO (FTO) ELISA Kit
BA7714-10	FTO-IN-3
BA7711-25	FTO-IN-8
HY-168483	FTO-IN-13
HY-179267	FTO-IN-16

FTO-IN-14

Related Products

Alternative Products

Popular Products